On 20th July, 1969, our world changed when humans walked on the surface of the moon for the first time. This pioneering achievement by Neil A. Armstrong, Buzz Aldrin, Michael Collins and all the engineers and teams of the Apollo 11 mission broadened our reality.
In 1977, Frederick Sanger and his colleagues Nicklen and Coulson introduced the chain-terminator method or dideoxy sequencing or simply Sanger sequencing as we know it. Similar to the moon landing, Sanger sequencing changed the world of biology and dominate the sequencing world for the next 30 years.
Just like Armstrong, Aldrin and Collins stood on the shoulders of giants such as Hans Lippershey and Galileo Galilei who invented the telescope (in 1608/1609), or the Russian cosmonaut Yuri Gagarin who was the first human in space (12th April 1961), Sanger and his colleagues also stood on the shoulders of giants!
Francis Crick, James Watson, Rosalind Franklin and Maurice Wilkins introduced the world to the double helical structure of DNA in 1953.
Robert Holley and colleagues were the first to sequence yeast transfer RNA (tRNA) using RNAses with base specificity in 1965.
Walter Fiers read the first ever DNA sequence of a whole gene – coding for a MS2 virus coating protein – in 1972.
“Scientific research is one of the most exciting and rewarding of occupations. It is like a voyage of discovery into unknown lands, seeking not for new territory but for new knowledge. It should appeal to those with a good sense of adventure”
– Fredrick Sanger
Since 1977, the world of genomics experienced many profound changes, most notable with the introduction of next generation sequencing based on the sequencing-by-synthesis method. Nowadays, genomics approaches are used to answer scientific questions in research, pharma and diagnostics, agriculture and food, biotechnology, and medical science.
The DNA Universe represents the sheer endless applications for genomics. For every research question in the field of genomics, Eurofins Genomics has a solution. Whether you need Sanger sequencing, primers and probes, next generation sequencing, synthetic genes, CRISPR, or cell line authentication and testing for Mycoplasma contaminations… The DNA Universe always provides the genomic tools for scientists to be explorers.